TPM2 as a potential predictive biomarker for atherosclerosis

Serum Uric Acid as a Potential Concomitant with Carotid Atherosclerosis

Background: Common carotid intima-media thickness (CC-IMT) measured by ultrasonography as a non-invasive method is nowadays known as a marker for early atherosclerosis. Objectives: Survey the relationship between serum uric acid and carotid intima-media thickness considering hypertension. Materials and Methods: This study was designed as a comparative cross-sectional study in northern Ira...

PD-L1 expression as a potential predictive biomarker.

S100β: A Predictive Biomarker for Neural Trauma with Therapeutic Potential

for making both diagnoses and prognoses of neurological injury. Of the more than 20 isoforms in the S100 protein family, S100ß displays unique biomarker and diagnostic properties in ectodermic derived normal neurons and certain malignancies. The purpose of this focused review is to highlight and discuss findings that support the notion that S100ß can be used as a biomarker to indicate the prese...

Circulating sortilin level as a potential biomarker for coronary atherosclerosis and diabetes mellitus

CONTEXT A previous genome-wide association study showed that a genetic variant of sortilin was associated with the risk of coronary artery disease (CAD). However, the role of circulating sortilin is still unknown. We investigated the potential role of plasma sortilin as a biomarker for CAD and diabetes mellitus. METHODS We enrolled statin-naïve subjects with CAD (n = 31) who underwent coronar...

LOX-1 protein, A Biomarker in the Prognosis of Atherosclerosis

LOX-1 is a class E scavenger receptor that mediates the uptake of oxLDL by vascular cells. LOX-1 is involved in endothelial dysfunctions, monocyte adhesion, the proliferation, migration, and apoptosis of smooth muscle cells, foam cell formation, platelet activation, as well as plaque instability; all of these events are critical in the pathogenesis of atherosclerosis. These LOX-1-dependent bio...